Resting-state functional connectivity reveals age-related difference in Valproate-induced rat autism model
This study demonstrates changes of functional connectivity in motor related brain areas and it is age-related different in Valproate-induced rat autism model. Our results indicate that the motor cortex and striatum may be crucial areas for treatment and evolution of ASD. rsfMRI has potential to explore functional connectivity in the brain and monitor functional plasticity changes in a specific neuroanatomical pathway in vivo.